Comparison of different silica microporous structures as drug delivery systems for in vitro models of solid tumors

Author:

Vilaça Natália12345ORCID,Machado Ana F.12345ORCID,Morais-Santos Filipa67385ORCID,Amorim Ricardo67385ORCID,Patrícia Neto A.12345ORCID,Logodin Enora12345ORCID,Pereira Manuel F. R.910111213ORCID,Sardo Mariana1415165ORCID,Rocha João1415165ORCID,Parpot Pier12345ORCID,Fonseca António M.12345ORCID,Baltazar Fátima67385ORCID,Neves Isabel C.12345ORCID

Affiliation:

1. Centre of Chemistry

2. Chemistry Department

3. University of Minho

4. 4710-057 Braga

5. Portugal

6. Life and Health Sciences Research Institute (ICVS)

7. School of Medicine

8. Braga

9. Laboratory of Catalysis and Materials (LCM)

10. Associate Laboratory LSRE-LCM

11. Faculdade de Engenharia

12. University of Porto

13. 4200-465 Porto

14. CICECO – Chemistry Department

15. University of Aveiro

16. 3810-193 Aveiro

Abstract

5-FU release profiles reveled to be dependent on the host structures. 5-FU DDS led to significant potentiation of the 5-FU effect in cancer cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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