Expanding the repertoire of GalNAc analogues for cell-specific bioorthogonal tagging of glycoproteins-Reference-Cited by-同舟云学术

Expanding the repertoire of GalNAc analogues for cell-specific bioorthogonal tagging of glycoproteins

Published:2024 Issue: Volume: Page:
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Zafar Abdul¹²^ORCID,Sridhar Sandhya¹²³^ORCID,Bineva-Todd Ganka¹^ORCID,Cioce Anna¹²^ORCID,Abdulla Nadia¹²,Chang Vincent⁴,Malaker Stacy A.⁴^ORCID,Hewings David S.⁵^ORCID,Schumann Benjamin¹²^ORCID

Affiliation:

1. Chemical Glycobiology Laboratory, The Francis Crick Institute, NW1 1AT London, UK

2. Department of Chemistry, Imperial College London, W12 0BZ London, UK

3. Tumour-Host Interaction Laboratory, The Francis Crick Institute, NW1 1AT London, UK

4. Department of Chemistry, Yale University, CT 06511 New Haven, USA

5. Vertex Pharmaceuticals (Europe) Ltd., 86-88 Jubilee Avenue, Milton Park, Abingdon, OX14 4RW Oxfordshire, UK

Abstract

Demonstrating the use of azide-containing GalNAc analogues in conjunction with an engineered metabolic pathway to study glycosylation cell-specifically.

Funder

Biotechnology and Biological Sciences Research Council

Medical Research Council

Cancer Research UK

Wellcome Trust

Engineering and Physical Sciences Research Council

National Institute of General Medical Sciences

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CB/D4CB00093E

Reference36 articles.

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2. A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems

3. Metabolic precision labeling enables selective probing of O-linkedN-acetylgalactosamine glycosylation

4. Metabolic glycoengineering – exploring glycosylation with bioorthogonal chemistry

5. Click Chemistry in Proteomic Investigations