DNA encoded peptide library for SARS-CoV-2 3CL protease covalent inhibitor discovery and profiling-Reference-Cited by-同舟云学术

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DNA encoded peptide library for SARS-CoV-2 3CL protease covalent inhibitor discovery and profiling

Published:2024 Issue:7 Volume:5 Page:691-702
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Xing Yuyu¹²,Zhang Huiya¹,Wang Yanhui¹,Zong Zhaoyun¹,Bogyo Matthew³^ORCID,Chen Shiyu¹²^ORCID

Affiliation:

1. Biotech Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

2. University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China

3. Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA

Abstract

DNA-encoded peptide covalent inhibitor library (DEPCIL) for discovering covalent inhibitors of protease and profiling active site preferences.

Funder

Chinese Academy of Sciences

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CB/D4CB00097H

Reference39 articles.

1. New functions for the matrix metalloproteinases in cancer progression

2. MEROPS: the peptidase database

3. Role of protease and protease inhibitors in cancer pathogenesis and treatment

4. Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration

5. m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration

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