Self-assembly pipette tip-based cigarette filters for micro-solid phase extraction of ketoconazole cis-enantiomers in urine samples followed by high-performance liquid chromatography/diode array detection-Reference-Cited by-同舟云学术

Self-assembly pipette tip-based cigarette filters for micro-solid phase extraction of ketoconazole cis-enantiomers in urine samples followed by high-performance liquid chromatography/diode array detection

Published:2015 Issue:17 Volume:7 Page:7270-7279
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Andrade Roseane Teixeira¹²³⁴,Santos da Silva Ricky Cássio¹²³⁴,Pereira Arnaldo César¹²³⁴,Borges Keyller Bastos¹²³⁴

Affiliation:

1. Departamento de Ciências Naturais

2. Universidade Federal de São João del-Rei

3. São João del-Rei

4. Brazil

Abstract

A simple stereoselective HPLC/DAD method was developed for the determination of ketoconazole (KTZ) cis-enantiomers in human urine.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/AY/C5AY00468C

Reference35 articles.

1. Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes.

2. Ketoconazole-associated hepatic injury

3. Stereoisomers of ketoconazole: preparation and biological activity

4. Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates

5. Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers

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