A self-amplifying nanodrug to manipulate the Janus-faced nature of ferroptosis for tumor therapy-Reference-Cited by-同舟云学术

A self-amplifying nanodrug to manipulate the Janus-faced nature of ferroptosis for tumor therapy

Published:2022 Issue:2 Volume:7 Page:198-210
ISSN:2055-6756
Container-title:Nanoscale Horizons
language:en
Short-container-title:Nanoscale Horiz.

Author:

Zhang Mengzhu¹,Qin Xiaohan¹,Zhao Zhipeng¹,Du Qian¹,Li Qian¹,Jiang Yue¹,Luan Yuxia¹^ORCID

Affiliation:

1. NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China

Abstract

A self-amplifying nanodrug was precisely designed to reprogram the Janus-faced nature of ferroptosis via harnessing the positive role of ferroptosis along with reversing its inherent negative role to achieve optimal ferroptotic tumor therapy.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NH/D1NH00506E

Reference40 articles.

1. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

2. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

3. Targeting Ferroptosis to Iron Out Cancer