Proximity-inducing modalities: the past, present, and future-Reference-Cited by-同舟云学术

Proximity-inducing modalities: the past, present, and future

Published:2023 Issue:16 Volume:52 Page:5485-5515
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Singh Sameek¹^ORCID,Tian Wenzhi¹^ORCID,Severance Zachary C.¹^ORCID,Chaudhary Santosh K.¹^ORCID,Anokhina Viktoriya¹^ORCID,Mondal Basudeb¹^ORCID,Pergu Rajaiah¹^ORCID,Singh Prashant¹^ORCID,Dhawa Uttam¹^ORCID,Singha Santanu¹^ORCID,Choudhary Amit¹²³^ORCID

Affiliation:

1. Chemical Biology and Therapeutics Science, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA

2. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA

3. Divisions of Renal Medicine and Engineering, Brigham and Women's Hospital, Boston, MA 02115, USA

Abstract

In this review, we highlight bifunctional modalities that perform functions other than degradation and have great potential to revolutionize disease treatment, while also serving as important tools in basic research to explore new aspects of biology.

Funder

National Institutes of Health

Defense Sciences Office, DARPA

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CS/D2CS00943A

Reference287 articles.

1. Join the crowd

2. Unifying principles of bifunctional, proximity-inducing small molecules