Pomegranate supplementation alleviates dyslipidemia and the onset of non-alcoholic fatty liver disease in Wistar rats by shifting microbiota and producing urolithin-like microbial metabolites-Reference-Cited by-同舟云学术

Pomegranate supplementation alleviates dyslipidemia and the onset of non-alcoholic fatty liver disease in Wistar rats by shifting microbiota and producing urolithin-like microbial metabolites

Published:2024 Issue:14 Volume:15 Page:7348-7363
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Sánchez-Terrón Guadalupe¹,Martínez Remigio²,Morcuende David¹,Caballero Víctor¹,Estévez Mario¹^ORCID

Affiliation:

1. TECAL Research Group, Meat and Meat Products Research Institute (IPROCAR), Universidad de Extremadura (UEX, ROR-ID 0174shg90), Cáceres, 10003, Spain

2. Animal Health Department, Animal Health and Zoonoses Research Group (GISAZ), UIC Zoonosis and Emergent Diseases (ENZOEM Competitive Research Unit), Universidad of Córdoba (UCO, ROR-ID 05yc77b46), Córdoba, 14014, Spain

Abstract

Pomegranate supplemetation decreased fat depots, counteracted the dyslipidemia caused by fructose and improved markers of liver injury. Microbial metabolites from pomegranate may be responsible for these health benefits.

Funder

Consejería de Educación y Empleo, Junta de Extremadura

Ministerio de Ciencia, Innovación y Universidades

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO00688G

Reference58 articles.

1. Guideline: Sugars Intake for Adults and Children , World Health Organization , Geneva , 2015

2. Molecular aspects of fructose metabolism and metabolic disease

3. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids

4. Glucose boosts protein oxidation/nitration during simulated gastric digestion of myofibrillar proteins by creating a severe pro-oxidative environment

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