Size-dependent tuning of horseradish peroxidase bioreactivity by gold nanoparticles-Reference-Cited by-同舟云学术

Size-dependent tuning of horseradish peroxidase bioreactivity by gold nanoparticles

Published:2015 Issue:10 Volume:7 Page:4505-4513
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Wu Haohao¹²³⁴⁵,Liu Yi⁴⁵⁶⁷⁸,Li Meng⁴⁵⁶⁷⁸,Chong Yu⁴⁵⁶⁷⁸,Zeng Mingyong¹²³,Lo Y. Martin⁹¹⁰⁸,Yin Jun-Jie⁴⁵⁶⁷⁸

Affiliation:

1. College of Food Science and Engineering

2. Ocean University of China

3. Qingdao, China

4. Division of Analytical Chemistry

5. Office of Regulatory Science

6. Center for Food Safety and Applied Nutrition

7. U.S. Food and Drug Administration

8. College Park, USA

9. Department of Nutrition and Food Science

10. University of Maryland

Abstract

Here we report gold nanoparticles can size-dependently enhance or inhibit HRP bioreactivity toward substrates with different redox potentials via a mechanism involving extension of the HRP substrate access channel and decline in the redox potentials of HRP catalytic intermediates.

Funder

China Scholarship Council

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NR/C4NR07056A

Reference48 articles.

1. Gold nanoparticles in biomedical applications: recent advances and perspectives

2. Biodistribution and toxicity of engineered gold nanoparticles: a review of in vitro and in vivo studies