Metal-free regioselective nitration of quinoxalin-2(1H)-ones with tert-butyl nitrite-Reference-Cited by-同舟云学术

Metal-free regioselective nitration of quinoxalin-2(1H)-ones with tert-butyl nitrite

Published:2021 Issue:48 Volume:19 Page:10554-10559
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Li Yi-Na¹,Li Xue-Lin²,Wu Jin-Bo¹,Jiang Hong¹,Liu Yunmei¹,Guo Yu¹^ORCID,Zeng Yao-Fu¹^ORCID,Wang Zhen¹^ORCID

Affiliation:

1. School of Pharmaceutical Science, Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China

2. The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China

Abstract

A metal-free regioselective nitration of quinoxalin-2(1H)-ones at the C5 or C7 position has been established, which was distinct from the previous functionalization of quinoxalin-2(1H)-ones.

Funder

Natural Science Foundation ofHunan Province

Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB02015C

Reference71 articles.

1. Quinoxalinone as a Privileged Platform in Drug Development

2. Chemistry, Biological Properties and SAR Analysis of Quinoxalinones