4-Phosphopyrazol-2-yl alanine: a non-hydrolysable analogue of phosphohistidine-Reference-Cited by-同舟云学术

4-Phosphopyrazol-2-yl alanine: a non-hydrolysable analogue of phosphohistidine

Published:2015 Issue:34 Volume:51 Page:7305-7308
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Lilley Matthew¹²³⁴⁵,Mambwe Bezaleel⁵⁶⁷³⁴,Thompson Mark J.¹²³⁴,Jackson Richard F. W.¹²³⁴,Muimo Richmond⁵⁶⁷³⁴

Affiliation:

1. Department of Chemistry

2. The University of Sheffield

3. Sheffield

4. UK

5. Department of Infection and Immunity

6. Academic Unit of Respiratory Medicine

7. The University of Sheffield Medical School

Abstract

We report the synthesis of a stable analogue of τ-phosphohistidine: 4-phosphopyrazol-2-yl alanine (pPza).

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC01811K

Reference27 articles.

1. Why nature chose phosphate to modify proteins

2. The regulation of protein function by multisite phosphorylation – a 25 year update

3. Isolation of [32P]phosphohistidine from different rat-liver cell fractions after incubation with [32P]adenosine triphosphate

4. Phosphohistidine

5. Focus on phosphohistidine

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