Surface specifically modified NK-92 cells with CD56 antibody conjugated superparamagnetic Fe3O4 nanoparticles for magnetic targeting immunotherapy of solid tumors-Reference-Cited by-同舟云学术

Surface specifically modified NK-92 cells with CD56 antibody conjugated superparamagnetic Fe3O4 nanoparticles for magnetic targeting immunotherapy of solid tumors

Published:2021 Issue:45 Volume:13 Page:19109-19122
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Zhao Songbo¹,Duan Jiazhi²,Lou Yalin¹,Gao Ruyun¹,Yang Shanshan¹,Wang Piming³,Wang Chunhua⁴,Han Lin⁴^ORCID,Li Minghuan⁵,Ma Chunhong¹,Liang Xiaohong¹,Liu Hong²^ORCID,Sang Yuanhua²^ORCID,Gao Lifen¹

Affiliation:

1. Key Laboratory for Experimental Teratology of Ministry of Education, Shandong Key Laboratory of Infection and Immunity, and Department of Immunology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, P. R. China

2. State Key Laboratory of Crystal Materials, Shandong University, Jinan, Shandong, 250100, P.R. China

3. Department of Clinical Laboratory, Shandong Provincial Corps Hospital of Chinese People's Armed Police Force, Jinan, Shandong, 250100, P.R. China

4. Institute of Marine Science and Technology, Shandong University, Qingdao, Shandong, 266000, P.R. China

5. Shandong Institute of cancer prevention and treatment, Jinan, Shandong, 250117, P.R. China

Abstract

Superparamagnetic Fe3O4 nanoparticles combined NK-92 cells could be attracted to the tumor site under the guidance of external magnetic field and effectively inhibit the tumor growth.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Natural Science Fund for Distinguished Young Scholars of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D1NR03329H

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1. Combinational strategy for high-performance cancer chemotherapy