Strategies for the preparation of non-amplified and amplified genomic dengue gene samples for electrochemical DNA biosensing applications

Author:

Abdul Rashid Jahwarhar Izuan1ORCID,Yusof Nor Azah2,Abdullah Jaafar2ORCID,Shomiad @ Shueb Rafidah Hanim3

Affiliation:

1. Department of Chemistry and Biology, Centre for Defence Foundation Studies, National Defence University of Malaysia, Sungai Besi Camp, 57000, Kuala Lumpur, Malaysia

2. Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor 43400, Malaysia

3. Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia

Abstract

The application of electrochemical DNA biosensors in real genomic sample detection is challenging due to the existence of complex structures and low genomic concentrations, resulting in inconsistent and low current signals.

Funder

Kementerian Sains, Teknologi dan Inovasi

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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