Mustard seed major allergen Sin a1 activates intestinal epithelial cells and also dendritic cells that drive type 2 immune responses-Reference-Cited by-同舟云学术

Mustard seed major allergen Sin a1 activates intestinal epithelial cells and also dendritic cells that drive type 2 immune responses

Published:2024 Issue:12 Volume:15 Page:6488-6501
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Bueno-Díaz Cristina¹^ORCID,Zuurveld Marit¹,Ayechu-Muruzabal Verónica¹,Korsten Sandra G. P. J.¹²,Martín-Pedraza Laura³,Parrón-Ballesteros Jorge⁴,Redegeld Frank¹,Garssen Johan¹⁵,Villalba Mayte⁴,Willemsen Linette E. M.¹^ORCID

Affiliation:

1. Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, The Netherlands

2. Tiofarma B.V., Oud-Beijerland, The Netherlands

3. Hospital Ramón y Cajal, Madrid, Spain

4. Department of Biochemistry and Molecular Biology, Complutense University of Madrid, Madrid, Spain

5. Danone Nutricia Research B.V., Utrecht, The Netherlands

Abstract

Mustard seed allergen Sin a1 may activate mucosal barrier human intestinal epithelial cells (A) and/or dendritic cells (B), to initiate allergic sensitization by allowing consecutive type 2 activation of DC/T-cells, T/B-cells, and/or mast cells.

Funder

Universidad Complutense de Madrid

Ministerio de Ciencia e Innovación

Federation of European Biochemical Societies

European Molecular Biology Organization

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO01980F

Reference59 articles.

1. Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management

2. Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?

3. The immune system and the gut microbiota: friends or foes?

4. Molecular and cellular mechanisms of food allergy and food tolerance

5. Food allergy: immune mechanisms, diagnosis and immunotherapy