Synthesis, DNA-binding and antiproliferative properties of diarylquinolizinium derivatives-Reference-Cited by-同舟云学术

Synthesis, DNA-binding and antiproliferative properties of diarylquinolizinium derivatives

Published:2021 Issue:4 Volume:19 Page:878-890
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Bortolozzi Roberta¹²³⁴⁵^ORCID,Ihmels Heiko⁶⁷⁸⁹^ORCID,Schulte Robin⁶⁷⁸⁹,Stremmel Christopher⁶⁷⁸⁹,Viola Giampietro¹²³⁴⁵^ORCID

Affiliation:

1. Department of Women's and Child's health

2. Oncohematology laboratory

3. University of Padova

4. I-35128 Padova

5. Italy

6. Department of Chemistry and Biology

7. University of Siegen

8. 57068 Siegen

9. Germany

Abstract

Diaryl-substituted quinolizinium derivatives constitute a promising class of readily available DNA binding and cytotoxic compounds with a relatively strong antiproliferative effect on selected tumor cells.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB02298E

Reference73 articles.

1. DNA binders in clinical trials and chemotherapy

2. DNA binding and Topoisomerase inhibition: How can these mechanisms be explored to design more specific anticancer agents?

3. Specific Recognition of DNA by Small Molecules

4. Chemical approaches to the discovery and development of cancer therapies

5. G. S. Goldberg and R.Airley , Cancer Chemotherapy: Basic Science to the Clinic , Wiley , Chichester , 2nd edn, 2020

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