Corn distillers solubles as a novel bioresource of bioactive peptides with ACE and DPP IV inhibition activity: characterization, <i>in silico</i> evaluation, and molecular docking-Reference-Cited by-同舟云学术

Corn distillers solubles as a novel bioresource of bioactive peptides with ACE and DPP IV inhibition activity: characterization, in silico evaluation, and molecular docking

Published:2022 Issue:15 Volume:13 Page:8179-8203
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Sharma Sonu¹^ORCID,Pradhan Ranjan¹²,Manickavasagan Annamalai¹,Thimmanagari Mahendra³,Dutta Animesh¹^ORCID

Affiliation:

1. School of Engineering, University of Guelph, Guelph, Ontario, Canada N1G 2W1

2. Shrimp Canada, 67 Watson Rd. S (Unit-2), Guelph, Ontario, N1L 1 E3, Canada

3. Food and Rural Affairs, Ontario Ministry of Agriculture, 1 Stone Road West, Guelph N1G 4Y1, Ontario, Canada

Abstract

Alcalase was found to be the best enzyme for CDS and the protein hydrolysates produced showed superior inhibition of ACE (98.76 ± 1.28%) and DPP IV (34.99 ± 1.44%). Bioinformatic tools demonstrated potential anti-ACE and anti-DPP IV peptides.

Funder

BioFuelNet Canada

Ontario Ministry of Agriculture, Food and Rural Affairs

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO04109F

Reference65 articles.

1. Generation of wheat gluten hydrolysates with dipeptidyl peptidase IV (DPP-IV) inhibitory properties

2. Exploration of rice protein hydrolysates and peptides with special reference to antioxidant potential: Computational derived approaches for bio-activity determination