Development of an optimized HPLC method for the simultaneous determination of six compounds containing β-lactam ring in human plasma and urine using experimental design methodology-Reference-Cited by-同舟云学术

Development of an optimized HPLC method for the simultaneous determination of six compounds containing β-lactam ring in human plasma and urine using experimental design methodology

Published:2016 Issue:12 Volume:6 Page:9465-9474
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Abdel Hameed Eman A.¹²³⁴⁵,Abdel Salam Randa A.¹²³⁴⁵,Hadad Ghada M.¹²³⁴⁵

Affiliation:

1. Pharmaceutical Analytical Chemistry Department

2. Faculty of Pharmacy

3. Suez Canal University

4. Ismailia 41522

5. Egypt

Abstract

β-Lactam antibiotics are commonly prescribed with β-lactamase inhibitors to patients, for that it is necessary to develop an optimized chromatographic method which determine them simultaneously in biological fluids.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA23350J

Reference37 articles.

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2. Simultaneous determination of amoxicillin and clavulanic acid in human plasma by isocratic reversed-phase HPLC using UV detection

3. Development and Validation of Stability Indicating HPLC Method for Simultaneous Estimation of Amoxicillin and Clavulanic Acid in Injection

4. Simultaneous analysis of amoxicillin and sulbactam in human plasma by HPLC-DAD for assessment of bioequivalence

5. Simultaneous determination of flucloxacillin and ampicillin in human plasma by ultra performance liquid chromatography–tandem mass spectrometry and subsequent application to a clinical study in healthy Chinese volunteers

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