Tracking nucleic acid nanocapsule assembly, cellular uptake and disassembly using a novel fluorescently labeled surfactant
Author:
Affiliation:
1. Department of Chemistry
2. University of Connecticut
3. Storrs
4. USA
Abstract
By introducing a solvatochromatic chromophore to a DNA–surfactant conjugate, the dynamics of its assembly and disassembly can be monitored using fluorescence spectroscopy.
Funder
University of Connecticut
National Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA09472B
Reference17 articles.
1. Gene-silencing technology gets first drug approval after 20-year wait
2. Oligonucleotides to the (Gene) Rescue: FDA Approvals 2017–2019
3. From micro to nano: evolution and impact of drug delivery in treating disease
4. Towards Self-Transfecting Nucleic Acid Nanostructures for Gene Regulation
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