Dual delivery of siRNA and plasmid DNA using mesoporous silica nanoparticles to differentiate induced pluripotent stem cells into dopaminergic neurons-Reference-Cited by-同舟云学术

Dual delivery of siRNA and plasmid DNA using mesoporous silica nanoparticles to differentiate induced pluripotent stem cells into dopaminergic neurons

Published:2017 Issue:16 Volume:5 Page:3012-3023
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Chang Jen-Hsuan¹²³⁴,Tsai Ping-Hsing⁵⁶⁷⁴,Chen Wei¹²³⁴,Chiou Shih-Hwa⁵⁶⁷⁴,Mou Chung-Yuan¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. National Taiwan University

3. Taipei 106

4. Taiwan

5. Department of Medical Research and Education

6. Taipei Veterans General Hospital

7. Taipei 112

Abstract

Nurr1 plasmid and Rex1 siRNA were complexed with positively charged FITC-conjugated mesoporous silica nanoparticles. The pNurr1–siRex1–FMSN(+) was delivered to induced pluripotent stem cells to enhance their differentiation into dopaminergic neurons.

Funder

Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C7TB00351J

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