Stent containing CD44-targeting polymeric prodrug nanoparticles that release paclitaxel and gemcitabine in a time interval-controlled manner for synergistic human biliary cancer therapy

Author:

Yun Dayeon1234,Kim Hyun-Ouk1234,Son Hye Young5264,Choi Yuna5264,Noh Ilkoo1784,Lim Jong-Woo1234,Kim Jihye1234,Chun Haejin1234,Park Geunseon1234,Lee Dong Ki91011124,Jang Sung Il91011124,Jang Eunji5264,Huh Yong-Min5264,Haam Seungjoo1234ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering

2. Yonsei University

3. Seoul 120-749

4. Republic of Korea

5. Department of Radiology

6. Seoul 120-752

7. Korea Advanced Institute of Science and Technology (KAIST)

8. Daejon 305-701

9. Department of Internal Medicine

10. Gangnam Severance Hospital

11. Yonsei University College of Medicine

12. Seoul 135-720

Abstract

The use of drug-eluting stents (DESs) is a promising strategy for non-vascular diseases, especially human biliary cancer.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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