Inflammatory modulation of stem cells by Magnetic Resonance Imaging (MRI)-detectable nanoparticles

Author:

Aday Sezin12345,Paiva Jose12345,Sousa Susana456,Gomes Renata S. M.78910,Pedreiro Susana113,So Po-Wah1213910,Carr Carolyn Ann14151617,Cochlin Lowri1819,Gomes Ana Catarina456,Paiva Artur113,Ferreira Lino12345

Affiliation:

1. CNC – Center for Neurosciences and Cell Biology

2. University of Coimbra

3. Coimbra, Portugal

4. Biocant

5. Biotechnology Innovation Center

6. , Portugal

7. King's BHF Centre of Excellence

8. Cardiovascular Proteomics

9. King's College London

10. London, UK

11. Centro de Histocompatibilidade do Centro

12. Department of Neuroimaging

13. Institute of Psychiatry

14. Cardiac Metabolism Research Group

15. Department of Physiology, Anatomy & Genetics

16. University of Oxford

17. UK

18. PulseTeq Limited

19. Surrey, UK

Abstract

Novel MRI-detectable PLGA nanoparticles can track hematopoietic stem cells and down-regulate the secretion of pro-inflammatory cytokines by interfering with TLRs.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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