Synthesis, molecular structure and electrochemical properties of nickel(ii) benzhydrazone complexes: influence of ligand substitution on DNA/protein interaction, antioxidant activity and cytotoxicity

Author:

Raj Kumar Ramasamy1234,Ramesh Rengan1234

Affiliation:

1. School of Chemistry

2. Bharathidasan University

3. Tiruchirappalli – 620 024

4. India

Abstract

Four new nickel(ii) benzhydrazone complexes were synthesized and characterized. The influence of ligand substitution on DNA/protein binding, antioxidant activity and cytotoxicity is described. The complexes are able to induce apoptosis in cancer cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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