Silver salts and DBU cooperatively catalyzed nucleophilic addition/cyclization of propargylic alcohols with trifluoromethyl ketones

Author:

Wang Jingjing1234,Kong Wei-Guang1234,Li Feng1234,Liu Jie1234,Shen Qin1234,Liu Lantao1234,Zhao Wen-Xian1234

Affiliation:

1. College of Chemistry and Chemical Engineering

2. Shangqiu Normal University

3. Shangqiu

4. China

Abstract

A general and efficient synthesis of trifluoromethyl substituted 5-alkylidene-1,3-dioxolane using a silver salt and DBU cooperatively catalyzed nucleophilic addition/cyclization of propargylic alcohols and trifluoromethyl ketones is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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