Synthesis, crystal structure, lipophilicity, antioxidant activity, binding interactions, and antibacterial activity against methicillin-resistant Staphylococcus aureus of a Ni(ii) Schiff base complex: combined theoretical and experimental approaches

Author:

Das Arpita1,Maity Ribhu2,Sarkar Tuhin3ORCID,Das Priyanka3,Brandao Paula4ORCID,Maity Tithi5,Sarkar Keka3,Samanta Bidhan Chandra2ORCID

Affiliation:

1. Department of Physics, Mugberia Gangadhar Mahavidyalaya, Bhupatinagar, Purba Medinipur 721425, West Bengal, India

2. Department of Chemistry, Mugberia Gangadhar Mahavidyalaya, Bhupatinagar, Purba Medinipur 721425, West Bengal, India

3. Department of Microbiology, University of Kalyani, West Bengal, India

4. Departamento de Química, CICECO, Universidade de Aveiro, 3810-193 Aveiro, Portugal

5. Department of Chemistry, Prabhat Kumar College, Purba Medinipur-721401, Contai, West Bengal, India

Abstract

Comprehensive biological properties of a Ni(ii) complex derived from N, O donor ligand against gram-positive Methicillin-resistant Staphylococcus aureus (MRSA) are reported; the complex demonstrates better antibacterial activity than the conventional antibiotic Cefoxitin.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

University of Kalyani

Fundação para a Ciência e a Tecnologia

Ministério da Ciência, Tecnologia e Ensino Superior

Publisher

Royal Society of Chemistry (RSC)

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