A microfluidic mechano-chemostat for tissues and organisms reveals that confined growth is accompanied with increased macromolecular crowding-Reference-Cited by-同舟云学术

A microfluidic mechano-chemostat for tissues and organisms reveals that confined growth is accompanied with increased macromolecular crowding

Published:2023 Issue:20 Volume:23 Page:4445-4455
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Ben Meriem Zacchari¹,Mateo Tiphaine¹,Faccini Julien¹,Denais Céline¹,Dusfour-Castan Romane²,Guynet Catherine²,Merle Tatiana³^ORCID,Suzanne Magali³,Di-Luoffo Mickaël⁴,Guillermet-Guibert Julie⁴⁵^ORCID,Alric Baptiste¹,Landiech Sylvain¹,Malaquin Laurent¹^ORCID,Mesnilgrente Fabien¹,Laborde Adrian¹,Mazenq Laurent¹,Courson Rémi⁶^ORCID,Delarue Morgan¹^ORCID

Affiliation:

1. LAAS-CNRS, Université de Toulouse, CNRS, Toulouse, France

2. Laboratoire de Microbiologie et de Génétique Moléculaires, Centre de Biologie Intégrative (CBI), CNRS, Université de Toulouse, F-31000, Toulouse, France

3. Molecular, Cellular and Developmental Biology unit (MCD), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, France

4. INSERM U1037, CRCT, Université de Toulouse, F-31037 Toulouse, France

5. Laboratoire d'Excellence TouCAN, F-31037 Toulouse, France

6. Ifremer, RDT, F-29280 Plouzané, France

Abstract

Structure sliding-elements allow for 3D culture of tissues, organisms or 3D multicellular organisms in microfluidic systems.

Funder

Institut National Du Cancer

Institut National de la Santé et de la Recherche Médicale

European Commission

Publisher

Royal Society of Chemistry (RSC)