Biocatalytic fumarate synthesis from pyruvate and CO2 as a feedstock

Author:

Takeuchi Mika1,Amao Yutaka12ORCID

Affiliation:

1. Graduate School of Science, Osaka Metropolitan University, 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka 558-8585, Japan

2. Research Centre of Artificial Photosynthesis (ReCAP), Osaka Metropolitan University, 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka 558-8585, Japan

Abstract

The biocatalytic synthesis of fumarate from CO2 and pyruvate vial-malate as an intermediate in an aqueous medium using a biocatalytic system consisting of malate dehydrogenase and fumarase in the presence of NADH is developed.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Reference29 articles.

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3. Tailoring of activity and selectivity using bimetallic catalyst in hydrogenation of succinic acid

4. I.Goldberg and J. S.Rokem , Fumaric Acid Biosynthesis and Accumulation , Wiley , Hoboken, New Jersey , 2014

5. K.Lohbeck , H.Haferkorn , W.Fuhrmann and N.Fedtke , “Maleic and fumaric Acids”, Ullmann's Encyclopedia of Industrial Chemistry , VCH , Weinheim, Germany , 2011 , vol. 40

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