Towards the development of mechanism-based biomarkers to diagnose drug hypersensitivity
Author:
Affiliation:
1. Instituto Politécnico Nacional
2. Unidad Profesional Interdisciplinaria de Biotecnología
3. Mexico City
4. Mexico
5. MRC Centre for Drug Safety Science
6. Department of Pharmacology
7. University of Liverpool
8. Liverpool
9. UK
Abstract
T-cells are activated by different mechanisms in the presence of drugs, metabolites or haptens, and they release several molecules that can be used in the diagnosis of drug hypersensitivity.
Funder
Instituto Politécnico Nacional
Publisher
Oxford University Press (OUP)
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
http://pubs.rsc.org/en/content/articlepdf/2015/TX/C4TX00238E
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