Improved electrochemical detection of a transthyretin synthetic peptide in the nanomolar range with a two-electrode system integrated in a glass/PDMS microchip
Author:
Affiliation:
1. CNRS
2. UMR 8235
3. LISE
4. Paris, France
5. Sorbonne Universités
6. Institut Galien Paris-Sud
7. UMR 8612
8. F-92290 Châtenay-Malabry, France
9. Univ Paris-Sud
10. Laboratoire de Photonique et de Nanostructures
11. UPR20
12. , France
Abstract
Differential pulse voltammetry with a 2-microelectrode set-up in microchip was adapted for quantifying peptide (CBI-PN) involved in the diagnosis of familial transthyretin amyloidosis detected at 0.4 V while the Fe(iii)/Fe(ii) redox couple appears at 0 V.
Publisher
Royal Society of Chemistry (RSC)
Subject
Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2014/LC/C4LC00240G
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