Chitosan coated curcumin nanocrystals augment pharmacotherapy via improved pharmacokinetics and interplay of NFκB, Keap1 and Nrf2 expression in Gram negative sepsis
Author:
Affiliation:
1. Pharmaceutics Division
2. Central Drug Research Institute
3. Lucknow 226031
4. India
5. Toxicology Division
Abstract
Chi-CUR-NC provides a viable approach for reducing mortality in cIAI associated Gram negative sepsis.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA06786C
Reference49 articles.
1. Sepsis: a need for new solutions
2. Chemopreventive and therapeutic effects of curcumin
3. V. P. Menon and A. R.Sudheer in The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease, Springer, 2007, pp. 105–125
4. Optimization of novel tocopheryl acetate nanoemulsions for parenteral delivery of curcumin for therapeutic intervention of sepsis
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