Interrogation of drug effects on HeLa cells by exploiting new AFM mechanical biomarkers-Reference-Cited by-同舟云学术

Interrogation of drug effects on HeLa cells by exploiting new AFM mechanical biomarkers

Published:2017 Issue:69 Volume:7 Page:43764-43771
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yun Xiaoling¹²³⁴⁵,Tang Mingjie⁵⁶⁷⁸⁴,Yang Zhongbo⁵⁶⁷⁸⁴,Wilksch Jonathan J.⁹¹⁰¹¹¹²,Xiu Peng¹³¹⁴¹⁵¹⁶⁴,Gao Haiyang¹²³⁴¹⁷,Zhang Feng¹²³⁴,Wang Huabin⁵⁶⁷⁸⁴^ORCID

Affiliation:

1. School of Life Science

2. Inner Mongolia Agricultural University

3. Hohhot 010018

4. China

5. Chongqing Key Laboratory of Multi-Scale Manufacturing Technology

6. Chongqing Institute of Green and Intelligent Technology

7. Chinese Academy of Sciences

8. Chongqing 400714

9. Department of Microbiology and Immunology

10. University of Melbourne

11. Parkville

12. Australia

13. Department of Engineering Mechanics

14. Soft Matter Research Center

15. Zhejiang University

16. Hangzhou 310027

17. Department of Biomedical Engineering

Abstract

New AFM mechanical biomarkers including cell brush length, adhesion work and the factor of viscosity are discovered for drug assays.

Funder

Chinese Academy of Sciences

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA06233H

Reference41 articles.

1. How to improve R&D productivity: the pharmaceutical industry's grand challenge

2. Drug discovery in pharmaceutical industry: productivity challenges and trends

3. Therapeutic Targets: Progress of Their Exploration and Investigation of Their Characteristics

4. Drug-Induced Changes of Cytoskeletal Structure and Mechanics in Fibroblasts: An Atomic Force Microscopy Study

5. Nanoscale monitoring of drug actions on cell membrane using atomic force microscopy

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