Three dimensional conjugation of recombinant N-cadherin to a hydrogel for in vitro anisotropic neural growth

Author:

Vega L. Johana C. M.1234,Lee Min Kyung52346,Qin Ellen C.5234,Rich Max5234,Lee Kwan Young12347,Kim Dong Hyun891011,Chung Hee Jung12347,Leckband Deborah E.123412,Kong Hyunjoon52346

Affiliation:

1. Neuroscience Program

2. University of Illinois at Urbana-Champaign

3. Urbana

4. USA

5. Department of Chemical and Biomolecular Engineering

6. Institute for Genomic Biology

7. Department of Molecular and Integrative Physiology

8. Department of Human and Culture Convergence Technology R&BD Group

9. Korea Institute of Industrial Technology

10. Ansan-si Gyeonggi-do

11. South Korea

12. Department of Chemistry

Abstract

Strategy to culture cells in a three dimensional microchanneled hydrogel conjugated with Fc-N-Cad.

Funder

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Reference31 articles.

1. Approaches to neural tissue engineering using scaffolds for drug delivery

2. M. L. Linne and T. O.Jalonen, Chapter Nine-Astrocyte–Neuron Interactions: from experimental research-based models to translational medicine, in Progress in Molecular Biology and Translational science, ed. K. T. Blackwell, Academic press, 2014, vol. 123, pp. 191–217

3. Neural Tissue Engineering: Strategies for Repair and Regeneration

4. Materials for central nervous system regeneration: bioactive cues

5. Engineering an Integrated Cellular Interface in Three-Dimensional Hydrogel Cultures Permits Monitoring of Reciprocal Astrocyte and Neuronal Responses

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