Graphene oxide films as a novel tool for the modulation of myeloid-derived suppressor cell activity in the context of multiple sclerosis-Reference-Cited by-同舟云学术

Graphene oxide films as a novel tool for the modulation of myeloid-derived suppressor cell activity in the context of multiple sclerosis

Published:2024 Issue:15 Volume:16 Page:7515-7531
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Camacho-Toledano Celia¹²,Machín-Díaz Isabel¹²,Lebrón-Galán Rafael¹,González-Mayorga Ankor³,Palomares Francisco J.⁴,Serrano María C.⁴^ORCID,Clemente Diego¹²⁵^ORCID

Affiliation:

1. Neuroimmune-Repair Group, Hospital Nacional de Parapléjicos (HNP), SESCAM, Finca La Peraleda s/n, 45071-Toledo, Spain

2. Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Carlos III Health Institute, Av. Monforte de Lemos, 3-5, 28029-Madrid, Spain

3. Laboratory of Interfaces for Neural Repair, Hospital Nacional de Parapléjicos, SESCAM, Finca La Peraleda s/n, 45071- Toledo, Spain

4. Instituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas (CSIC), Calle Sor Juana Inés de la Cruz 3, 28049-Madrid, Spain

5. Design and development of biomaterials for neural regeneration, HNP, Associated Unit to CSIC through ICMM, Finca La Peraleda s/n, 45071-Toledo, Spain

Abstract

The biology of myeloid-derived suppressor cells (MDSCs) can be modified when grown on reduced graphene oxide (rGO) films. A higher oxidation state and roughness of rGO deplete MDSC activity by impacting on cell viability.

Funder

Ministerio de Economía y Competitividad

Instituto de Salud Carlos III

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NR/D3NR05351B

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