A drug discovery approach based on comparative transcriptomics between two toxin-secreting marine annelids: <i>Glycera alba</i> and <i>Hediste diversicolor</i>-Reference-Cited by-同舟云学术

A drug discovery approach based on comparative transcriptomics between two toxin-secreting marine annelids: Glycera alba and Hediste diversicolor

Published:2022 Issue:8 Volume:18 Page:731-744
ISSN:2515-4184
Container-title:Molecular Omics
language:en
Short-container-title:Mol. Omics

Author:

Moutinho Cabral Inês¹²^ORCID,Madeira Carolina¹²^ORCID,Grosso Ana R.¹²^ORCID,Costa Pedro M.¹²^ORCID

Affiliation:

1. Associate Laboratory i4HB – Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University of Lisbon, 2829-516 Caparica, Portugal

2. UCIBIO – Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, 2829-516 Caparica, Portugal

Abstract

While Glycera alba secretes neurotoxins, Hediste diversicolor may secrete fewer toxins with a broader action. Transcriptomics and human interactome-directed analysis unraveled promising candidates for biomedical applications from either annelid.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Genetics,Molecular Biology,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/MO/D2MO00138A

Reference73 articles.

1. Drug development from marine natural products

2. Marketed Marine Natural Products in the Pharmaceutical and Cosmeceutical Industries: Tips for Success

3. The hidden biotechnological potential of marine invertebrates: The Polychaeta case study