Crossing the blood–brain barrier with carbon dots: uptake mechanism and in vivo cargo delivery-Reference-Cited by-同舟云学术

Crossing the blood–brain barrier with carbon dots: uptake mechanism and in vivo cargo delivery

Published:2021 Issue:13 Volume:3 Page:3942-3953
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Seven Elif S.¹²³⁴^ORCID,Seven Yasin B.⁵⁶⁷⁴⁸,Zhou Yiqun¹²³⁴^ORCID,Poudel-Sharma Sijan⁹²³⁴,Diaz-Rucco Juan J.¹²³⁴,Kirbas Cilingir Emel¹²³⁴^ORCID,Mitchell Gordon S.⁵⁶⁷⁴⁸,Van Dyken J. David⁹²³⁴,Leblanc Roger M.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Miami

3. Coral Gables

4. USA

5. Department of Physical Therapy

6. University of Florida

7. Gainesville

8. McKnight Brain Institute

9. Department of Biology

Abstract

Glucose-based carbon dots (GluCDs) can cross blood–brain barrier in zebrafish and rat after intravenous injections and accumulate in neurons in rat CNS. Cell uptake of GluCDs involve glucose transporter proteins in a budding yeast model.

Funder

National Science Foundation

National Institutes of Health

University of Miami

University of Florida

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NA/D1NA00145K

Reference52 articles.