A liquid chromatography-tandem mass spectrometry method for the quantitation of imidafenacin in human plasma: application to a clinical pharmacokinetic study
Author:
Affiliation:
1. Center of Drug Metabolism and Pharmacokinetics
2. China Pharmaceutical University
3. Nanjing 210009
4. China
5. Department of Phase I Clinical Trials
6. Affiliated Nanjing University Medical College
7. Nanjing 210008
Abstract
Assessment of the matrix effect by a post-column infusion method and sufficient matrix–analyte separation with a Synergi 4 μm Hydro-RP.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/AY/C6AY00647G
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2. Antimuscarinics and the Overactive Detrusor—Which Is the Main Mechanism of Action?
3. Overactive Bladder: A Better Understanding of Pathophysiology, Diagnosis and Management
4. Diagnosis and Treatment of Overactive Bladder (Non-Neurogenic) in Adults: AUA/SUFU Guideline Amendment
5. Selective Binding of Bladder Muscarinic Receptors in Relation to the Pharmacokinetics of a Novel Antimuscarinic Agent, Imidafenacin, to Treat Overactive Bladder
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