A simple, rapid and low-cost spectrophotometric method for irinotecan quantification in human plasma and in pharmaceutical dosage forms-Reference-Cited by-同舟云学术

A simple, rapid and low-cost spectrophotometric method for irinotecan quantification in human plasma and in pharmaceutical dosage forms

Published:2021 Issue:2 Volume:13 Page:258-266
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Tsotsou Georgia Eleni¹²³⁴⁵^ORCID,Gkotzamani Panagiota¹²³⁴⁵,Petro Victoria¹²³⁴⁵,Argyropoulou Ariadne¹²³⁴⁵,Karkalousos Petros¹²³⁴⁵

Affiliation:

1. Laboratory of Chemistry, Biochemistry and Cosmetology

2. Department of Biomedical Sciences

3. University of West Attica

4. Egaleo 122 43

5. Greece

Abstract

We are proposing the first widely applicable spectrophotometric method, after minimal pretreatment, for irinotecan quantification in plasma, to guide personalized dose adjustment and for quality control of irinotecan bulk or injection dosage.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AY/D0AY02201B

Reference27 articles.

1. Clinical Pharmacokinetics of Irinotecan

2. Sparse-data set analysis for irinotecan and SN-38 pharmacokinetics in cancer patients co-treated with cisplatin

3. Development and Validation of a High-Performance Liquid Chromatography–Tandem Mass Spectrometry Method for the Simultaneous Determination of Irinotecan and Its Main Metabolites in Human Plasma and Its Application in a Clinical Pharmacokinetic Study

4. Individualization of Irinotecan Treatment: A Review of Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics

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