Alkali halides as nucleophilic reagent sources for N-directed palladium-catalysed ortho-C–H halogenation of s-tetrazines and other heteroaromatics

Author:

Daher Ahmad1,Abidi Oumaima1,Hierso Jean-Cyrille1ORCID,Roger Julien1ORCID

Affiliation:

1. Institut de Chimie Moléculaire de l′Université de Bourgogne (UMR-CNRS 6302), Université Bourgogne Franche-Comté (UBFC), 9 Avenue Alain Savary 21078 Dijon, France

Abstract

A general palladium-catalysed selective C–H halogenation reaction is reported, which was successfully achieved for a large variety of functionalized aromatic rings incorporating diverse N-directing groups.

Funder

Centre National de la Recherche Scientifique

Université de Bourgogne

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference39 articles.

1. T. Kosjek , E. Heath , J. Iskra , ed. Springer , New York , Halogenated Heterocycles , 2012

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5. J.Clayden , N.Greeves , S.Warren , Organic Chemistry , Oxford University Press , Oxford , 2nd edn, 2012 , pp. 471–497

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