Negating coordinative cysteine and methionine residues during metathesis of unprotected peptides-Reference-Cited by-同舟云学术

Negating coordinative cysteine and methionine residues during metathesis of unprotected peptides

Published:2023 Issue:45 Volume:59 Page:6917-6920
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Thomson Amy L.¹^ORCID,Gleeson Ellen C.¹,Belgi Alessia¹^ORCID,Jackson W. Roy¹,Izgorodina Ekaterina I.¹^ORCID,Robinson Andrea J.¹^ORCID

Affiliation:

1. School of Chemistry, Monash University, Clayton 3800, Victoria, Australia

Abstract

In-situ masking of sulfur-containing residues ensures productive Ru-alkylidene catalysed olefin metathesis to generate metabolically stable cystine bridge peptidomimetics with defined geometry.

Funder

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC01476B

Reference33 articles.

1. Application of Ring-Closing Metathesis to the Synthesis of Rigidified Amino Acids and Peptides

2. Synthesis of Biologically Active Dicarba Analogues of the Peptide Hormone Oxytocin Using Ring-Closing Metathesis

3. Ring-closing metathesis in peptides

4. Microwave-assisted RCM for the synthesis of carbocyclic peptides

5. A simple amine protection strategy for olefinmetathesis reactions

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Anionic Olefin Metathesis Catalysts Enable Modification of Unprotected Biomolecules in Water;ACS Catalysis;2024-07-11

2. Synthesis of Cystine-Stabilised Dicarba Conotoxin EpI: Ring-Closing Metathesis of Sidechain Deprotected, Sulfide-Rich Sequences;Marine Drugs;2023-06-29

3. A tunable family of CAAC-ruthenium olefin metathesis catalysts modularly derived from a large-scale produced ibuprofen intermediate;Chemical Science;2023