C(sp2)–H functionalization of aldehyde-derived hydrazones via a radical process-Reference-Cited by-同舟云学术

C(sp2)–H functionalization of aldehyde-derived hydrazones via a radical process

Published:2018 Issue:8 Volume:16 Page:1227-1241
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Xu Xiaoyan¹²³⁴,Zhang Jun⁵⁶⁷⁴,Xia Hongguang¹²³⁴,Wu Jie⁵⁶⁷⁴⁸^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology

2. Zhejiang University School of Medicine

3. Hangzhou 310058

4. China

5. Department of Chemistry

6. Fudan University

7. Shanghai 200433

8. State Key Laboratory of Organometallic Chemistry

Abstract

This review is focused on the recent advances in the C(sp²)–H functionalization of aldehyde-derived hydrazones via a radical process. Diverse substituted hydrazones including N-heterocycles are afforded under mild conditions with excellent selectivities. In general, an aminyl radical as the key intermediate is involved during the reaction process.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00056E

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3. N,N-Dialkylhydrazones in Organic Synthesis. From Simple N,N-Dimethylhydrazones to Supported Chiral Auxiliaries