Organocatalytic asymmetric synthesis of benzazepinoindole derivatives with trifluoromethylated quaternary stereocenters by chiral phosphoric acid catalysts-Reference-Cited by-同舟云学术

Organocatalytic asymmetric synthesis of benzazepinoindole derivatives with trifluoromethylated quaternary stereocenters by chiral phosphoric acid catalysts

Published:2018 Issue:8 Volume:16 Page:1367-1374
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Rahman Abdul¹²³⁴⁵,Xie En¹²³⁴⁵,Lin Xufeng¹²³⁴⁵^ORCID

Affiliation:

1. Laboratory of Asymmetric Catalysis and Synthesis

2. Department of Chemistry

3. Zhejiang University

4. Hangzhou 310027

5. China

Abstract

An enantioselective aza-Friedel–Crafts reaction of trifluoromethyl dihydrobenzoazepinoindoles with pyrroles or indoles catalyzed by a chiral spirocyclic phosphoric acid was developed.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00055G

Reference79 articles.

1. Synthesis of Benzazepine Alkaloids and Related Compounds

2. Chemistry and biological activity of new 3-benzazepines

3. Synthesis and Applicability of Partially Reduced 2- Benzazepines