Experimental results and computational insight into sequential reactions of β-(2-aminophenyl)-α,β-ynones with aryl isocyanates/benzoyl isothiocyanate-Reference-Cited by-同舟云学术

Experimental results and computational insight into sequential reactions of β-(2-aminophenyl)-α,β-ynones with aryl isocyanates/benzoyl isothiocyanate

Published:2020 Issue:16 Volume:18 Page:3177-3189
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Arcadi Antonio¹²³^ORCID,Aschi Massimiliano¹²³^ORCID,Chiarini Marco⁴⁵⁶³^ORCID,Marinelli Fabio¹²³,Marsicano Vincenzo¹²³,Portalone Gustavo⁷⁸⁹³

Affiliation:

1. Dipartimento di Scienze Fisiche e Chimiche Università degli Studi di L'Aquila

2. 67100 Coppito

3. Italy

4. Facoltà di Bioscienze e Tecnologie Agro-alimentari e Ambientali

5. Università di Teramo

6. 64100 Teramo

7. Dipartimento di Chimica

8. Sapienza Università di Roma

9. 00185 Roma

Abstract

The selective formation of quinazoline vs. benzoxazine and benzothiazine derivatives from β-(2-aminophenyl)-α,β-ynones and aryl isocyanates/benzoyl isothiocyanate was explored. DFT calculations provide a plausible rationale.

Funder

Università degli Studi dell'Aquila

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00087F

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