Developing an advanced gut on chip model enabling the study of epithelial cell/fibroblast interactions-Reference-Cited by-同舟云学术

Developing an advanced gut on chip model enabling the study of epithelial cell/fibroblast interactions

Published:2021 Issue:2 Volume:21 Page:365-377
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Verhulsel Marine¹²³⁴⁵,Simon Anthony¹²⁶⁵⁷,Bernheim-Dennery Moencopi¹²³⁴⁵,Gannavarapu Venkata Ram¹²⁶⁵⁷,Gérémie Lauriane¹²³⁴⁵,Ferraro Davide¹²³⁴⁵^ORCID,Krndija Denis¹²⁶⁵⁷,Talini Laurence²⁸⁹¹⁰⁵^ORCID,Viovy Jean-Louis¹²³⁴⁵,Vignjevic Danijela Matic¹²⁶⁵⁷,Descroix Stéphanie¹²³⁴⁵^ORCID

Affiliation:

1. Institut Curie

2. CNRS

3. UMR 168

4. IPGG

5. PSL Research University

6. UMR 144

7. F-75005 Paris

8. UMR 7615

9. ESPCI Paris

10. UPMC, Sorbonne-Universités

Abstract

We report on a new gut on chip combining the co-culture of primary epithelial and stromal cells in 3D biomimetic scaffold. Proper segregation of dividing and differentiated cells along the crypt-villus axis was achieved in these unique conditions.

Funder

Fondation ARC pour la Recherche sur le Cancer

H2020 European Research Council

Agence Nationale de la Recherche

Institut National de la Santé et de la Recherche Médicale

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/LC/D0LC00672F

Reference50 articles.