Double-headed nucleic acids condense the molecular information of DNA to half the number of nucleotides-Reference-Cited by-同舟云学术

Double-headed nucleic acids condense the molecular information of DNA to half the number of nucleotides

Published:2021 Issue:72 Volume:57 Page:9128-9131
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Beck Kasper M.¹^ORCID,Sharma Pawan K.²,Hornum Mick¹^ORCID,Risgaard Nikolaj A.¹,Nielsen Poul¹^ORCID

Affiliation:

1. Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, Odense DK-5230, Denmark

2. Department of Chemistry, Kurukshetra University, Kurukshetra, 136119, India

Abstract

Double-headed nucleotides, holding two functional nucleobases each, successfully condense the molecular information of DNA to half the number of phosphates while drastically increasing duplex stability.

Funder

Natur og Univers, Det Frie Forskningsråd

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D1CC03539H

Reference16 articles.

1. Recent progress in non-native nucleic acid modifications

2. Biological applications of xeno nucleic acids

3. DNA-inspired oligomers: from oligophosphates to functional materials

4. Towards XNA nanotechnology: new materials from synthetic genetic polymers

5. Double-Headed Nucleotides: Building Blocks for New Nucleic Acid Architectures

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1. Observability of fidelity decay at the Lyapunov rate in few-qubit quantum simulations;Quantum;2022-09-08

2. Double-Headed 2′-Deoxynucleotides That Hybridize to DNA and RNA Targets via Normal and Reverse Watson–Crick Base Pairs;The Journal of Organic Chemistry;2022-04-01

3. Orthogonal Amplification Circuits Composed of Acyclic Nucleic Acids Enable RNA Detection;Journal of the American Chemical Society;2022-03-08

4. Double‐Headed Nucleotides with Increased Base‐Pairing Affinity and Specificity;European Journal of Organic Chemistry;2021-12-22