Is AI essential? Examining the need for deep learning in image-activated sorting of Saccharomyces cerevisiae

Author:

Hayashi Mika1ORCID,Ohnuki Shinsuke2ORCID,Tsai Yating2,Kondo Naoko2,Zhou Yuqi1,Zhang Hongqian1,Ishii Natsumi Tiffany1ORCID,Ding Tianben1ORCID,Herbig Maik1ORCID,Isozaki Akihiro13ORCID,Ohya Yoshikazu24ORCID,Goda Keisuke1567ORCID

Affiliation:

1. Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan

2. Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8562, Japan

3. Department of Mechanical Engineering, College of Science and Engineering, Ritsumeikan University, Shiga 525-8577, Japan

4. Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Tokyo 113-8654, Japan

5. Department of Bioengineering, University of California, Los Angeles, California 90095, USA

6. Institute of Technological Sciences, Wuhan University, Wuhan 430072, China

7. CYBO, Tokyo 135-0064, Japan

Abstract

We experimentally justify the advantages of jumping on the deep learning trend for image-activated budding yeast sorting and validate its applicability towards morphology-based yeast mutant screening.

Funder

Japan Society for the Promotion of Science

Konica Minolta Imaging Science Foundation

Council for Science, Technology and Innovation

Institute for Fermentation, Osaka

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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