Evaluation of ferrocenyl phosphines as potent antimalarials targeting the digestive vacuole function of Plasmodium falciparum-Reference-Cited by-同舟云学术

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Evaluation of ferrocenyl phosphines as potent antimalarials targeting the digestive vacuole function of Plasmodium falciparum

Published:2019 Issue:3 Volume:48 Page:1108-1117
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Subramanian Gowtham¹²³⁴^ORCID,Sadeer Abdul⁵⁶⁷⁴,Mukherjee Kalyani¹²³⁴,Kojima Tadayuki⁵⁶⁷⁴,Tripathi Pallavi¹²³⁴,Naidu Renugah¹²³⁴,Tay Shan Wen⁵⁶⁷⁴,Pang Jia Hao⁵⁶⁷⁴,Pullarkat Sumod A.⁵⁶⁷⁴^ORCID,Chandramohanadas Rajesh¹²³⁴^ORCID

Affiliation:

1. Pillar of Engineering Product Development (EPD)

2. Singapore University of Technology and Design (SUTD)

3. Singapore 487372

4. Singapore

5. Division of Chemistry & Biological Chemistry

6. School of Physical and Mathematical Sciences

7. Nanyang Technological University Singapore

Abstract

Ferrocenyl phosphines targeting the digestive vacuole function of the malaria parasite, Plasmodium falciparum.

Funder

Ministry of Education - Singapore

Nanyang Technological University

Agency for Science, Technology and Research

Singapore University of Technology and Design

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/DT/C8DT04263B

Reference60 articles.

1. Chemotherapy for Falciparum Malaria: The Armoury, the Problems and the Prospects

2. Antimalarial drug resistance in Africa: key lessons for the future

3. Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

4. Artemisinin Resistance inPlasmodium falciparumMalaria

5. Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria.

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1. An overview of auric compounds as antimalarial agents and their action against essential targets of the parasite;Coordination Chemistry Reviews;2024-03

2. Chemically induced phenotypes during the blood stage development of Plasmodium falciparum as indicators of the drug mode of action;Frontiers in Drug Discovery;2022-10-12

3. Methods Used to Investigate the Plasmodium falciparum Digestive Vacuole;Frontiers in Cellular and Infection Microbiology;2022-01-13

4. A comprehensive review on classifying fast-acting and slow-acting antimalarial agents based on time of action and target organelle of Plasmodium sp;Pathogens and Disease;2022

5. Hemozoin (beta-hematin) formation inhibitors; A promising target for the development of new antimalarials: Current update and A future prospect;Combinatorial Chemistry & High Throughput Screening;2021-09-24

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