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Chemical modulation of transcription factors

Published:2018 Issue:8 Volume:9 Page:1249-1272
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Wiedemann Bianca¹²³⁴,Weisner Jörn¹²³⁴,Rauh Daniel¹²³⁴^ORCID

Affiliation:

1. Technische Universität Dortmund

2. Fakultät für Chemie und Chemische Biologie

3. D-44227 Dortmund

4. Germany

Abstract

The diverse class of transcription factors has been associated with various diseases while remaining challenging targets for therapy.

Funder

Deutsche Forschungsgemeinschaft

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00273H

Reference219 articles.

1. Transcription factors as targets for cancer therapy

2. How many drug targets are there?

3. Ruxolitinib: A Review of Its Use in Patients with Myelofibrosis

4. Efficacy and safety of tofacitinib for moderate-to-severe plaque psoriasis: a systematic review and meta-analysis of randomized controlled trials

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1. Phenotypic screen identifies FOXO inhibitor to counteract maturation and promote expansion of human iPS cell-derived cardiomyocytes;Bioorganic & Medicinal Chemistry;2022-07

2. Current strategies and progress for targeting the “undruggable” transcription factors;Acta Pharmacologica Sinica;2022-02-07

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