Study and application of graphene oxide in the synthesis of 2,3-disubstituted quinolines via a Povarov multicomponent reaction and subsequent oxidation

Author:

Caputo Samantha1ORCID,Kovtun Alessandro2ORCID,Bruno Francesco345,Ravera Enrico3456ORCID,Lambruschini Chiara1ORCID,Melucci Manuela2ORCID,Moni Lisa1ORCID

Affiliation:

1. Department of Chemistry and Industrial Chemistry, University of Genoa, Via Dodecaneso 31, 16146 GENOVA, Italy

2. Consiglio Nazionale delle Ricerche, Istituto per la Sintesi Organica e la Fotoreattività (CNR-ISOF), Via Gobetti 101, 40129 BOLOGNA, Italy

3. Magnetic Resonance Center (CERM), University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy

4. Department of Chemistry “Ugo Schiff”, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Italy

5. Consorzio Interuniversitario Risonanze Magnetiche di Metalloproteine (CIRMMP), Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy

6. Florence Data -scienze, University of Florence, Italy

Abstract

Graphene oxide is exploited as a heterogeneous, metal-free and sustainable catalyst for the three-component Povarov reaction and subsequent oxidation. The multistep synthesis can also be performed as a one-pot procedure.

Funder

Graphene Flagship

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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