Synthesis and biological evaluation of palmyrolide A macrocycles as sodium channel blockers towards neuroprotection-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of palmyrolide A macrocycles as sodium channel blockers towards neuroprotection

Published:2016 Issue:36 Volume:14 Page:8457-8473
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Philkhana Satish Chandra¹²³⁴⁵,Mehrotra Suneet⁶⁷⁸⁹¹⁰,Murray Thomas F.⁶⁷⁸⁹¹⁰,Reddy D. Srinivasa¹²³⁴⁵

Affiliation:

1. CSIR-National Chemical Laboratory

2. Pune

3. India

4. Academy of Scientific and Innovative Research (AcSIR)

5. New Delhi

6. Department of Pharmacology

7. School of Medicine

8. Creighton University

9. Omaha

10. USA

Abstract

A detailed account on total synthesis, analogue synthesis, biological evaluation and SAR of palmyrolide A macrocycles towards sodium channel inhibition is reported.

Funder

Council for Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01372D

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