Rational design of protein–protein interaction inhibitors-Reference-Cited by-同舟云学术

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Rational design of protein–protein interaction inhibitors

Published:2015 Issue:1 Volume:6 Page:51-60
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Rognan Didier¹²³⁴⁵

Affiliation:

1. Laboratory for Therapeutical Innovation

2. UMR7200 CNRS-Université de Strasbourg

3. MEDALIS Drug Discovery Center

4. 67400 Illkirch

5. France

Abstract

Low molecular weight compound competing for the binding of the p53 tumor suppressor to the MDM2 oncoprotein.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C4MD00328D

Reference89 articles.

1. http://www.uniprot.org/uniprot/?query=organism%3A9606+AND+keyword:%22Complete+proteome+[KW-0181]%22, (accessed 17/07/2014)

2. How many drug targets are there?

3. Twenty years of protein interaction studies for biological function deciphering

4. An empirical framework for binary interactome mapping

5. Estimating the size of the human interactome

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