Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes
Author:
Affiliation:
1. Department of Health Toxicology
2. Xiangya School of Public Health
3. Central South University
4. Changsha 410078
5. PR China
Abstract
Previous evidence revealed significant elevated liver cancer mortality in the areas where water was contaminated with hexavalent chromium [Cr(vi)], which highlighted that we should pay more attention to Cr(vi)-induced cytotoxicity in hepatocytes.
Funder
National Natural Science Foundation of China
Publisher
Oxford University Press (OUP)
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
http://pubs.rsc.org/en/content/articlepdf/2019/TX/C8TX00231B
Reference33 articles.
1. Toxicity and Carcinogenicity of Chromium Compounds in Humans
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4. Oxidative stress, DNA damage, and antioxidant enzyme activity induced by hexavalent chromium in Sprague-Dawley rats
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