A strategy for synthesis of lipid nanoparticles using microfluidic devices with a mixer structure-Reference-Cited by-同舟云学术

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A strategy for synthesis of lipid nanoparticles using microfluidic devices with a mixer structure

Published:2015 Issue:57 Volume:5 Page:46181-46185
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Maeki Masatoshi¹²³⁴⁵,Saito Tatsuyoshi⁶³⁴⁵,Sato Yusuke⁷³⁸⁵,Yasui Takao⁹¹⁰¹¹¹²⁵,Kaji Noritada⁹¹⁰¹¹¹²⁵,Ishida Akihiko¹²³⁴⁵,Tani Hirofumi¹²³⁴⁵,Baba Yoshinobu⁹¹⁰¹¹¹²⁵,Harashima Hideyoshi⁷³⁸⁵,Tokeshi Manabu¹²³⁴⁵

Affiliation:

1. Division of Biotechnology and Macromolecular Chemistry

2. Faculty of Engineering

3. Hokkaido University

4. Sapporo 060-8628

5. Japan

6. Graduate School of Chemical Sciences and Engineering

7. Faculty of Pharmaceutical Sciences

8. Sapporo 060-0812

9. Department of Applied Chemistry

10. Graduate School of Engineering

11. Nagoya University

12. Nagoya 464-8603

Abstract

Formation behavior was discussed for lipid nanoparticles (LNPs) in the microfluidic devices equipped with different cycle numbers of the micromixers.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA04690D

Reference35 articles.

1. Non-viral vectors for gene-based therapy

2. Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer

3. Lipid-based nanoparticles in the systemic delivery of siRNA

4. Emerging Research and Clinical Development Trends of Liposome and Lipid Nanoparticle Drug Delivery Systems

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